Klik her for at downloade arbejdspapirer !

Shaken, not Stirred: The Re-Combinatorial Capacity of High-Tech Regions

by Henrich Dahlgren and Finn Valentin, Research Centre on Biotech Business

Innovative Scope in Biotech Business: Effects of Aligning Partner Types with the Firm's Science Base

by Toke Reichstein and Finn Valentin, Research Centre on Biotech Business

Shaken not Stirred: Multinational Takeovers in Sweden's Pharmaceutical Industry

[N.B. Newer version of this paper is found as working paper 2008-01]

by Henrich Dahlgren and Finn Valentin, Research Centre on Biotech Business

How do Resource and Industry Constraints Affect Firms’ Patenting Choices? Experiences of Small Danish Biotech Firms

[This paper has been submitted to a journal and is no longer accessible as a working paper.]

The Imprint of Founders on Biotech Firms

by Finn Valentin and Rasmus Lund Jensen, Research Centre on Biotech Business

Alliances of Scandinavian Biotech Start-Ups and their Effects on Financial Performance

by Finn Valentin and Henrich Dahlgren, Research Centre on Biotech Business

Valuation of a New Drug Candidate Using Decision Tree Analysis Exemplified by NB S101 of Osteologix A/S

by Michael Viscovich* and Christian Krogsgaard', *PhaseOneTrials A/S and 'Dong A/S

Academic-Business Cooperations in Biotechnology: Who Cooperates with Firms, and Why?

by Lee Davis* and Peter Lotz', *Research Centre on Biotech Business and 'IVS, Copenhagen Business School

Structure, employment and performance in biotech firms: Comparison of Danish and Swedish drug discovery firms

by Finn Valentin, Henrich Dahlgren and Rasmus Lund Jensen, Research Centre on Biotech Business

Growth Dynamics of Dedicated Biotechnology Firms in Transition Economies: Evidence from the Baltic Countries and Poland

By Stéphane Malo and Jesper Norus, Research Centre on Biotech Business, Copenhagen Business School

Effects on Academia-Industry Collaboration of Extending University Property Rights

By Finn Valentin and Rasmus Lund Jensen, Research Centre on Biotech Business, Copenhagen Business School

Research Strategies in Science-based Start-ups: Effects on Performance in Danish and Swedish Biotechnology

by Finn Valentin, Henrich Dahlgren and Rasmus Lund Jensen, Research Centre on Biotech Business

Patent Assessment Quality: Analyzing the Consistency of the EPO's Ruling on Novelty and Inventive Step in Emerging Industries

by Paul F. Burke* and Markus Retzig', * University of Technology, School of Marketing, Sydney and 'Research Centre on Biotech Business, Copenhagen Business School

Neutrons and Innovations: What Benefits will Denmark Obtain for its Science, Technology and Competitiveness by Co-hosting an Advanced Large-scale Research Facility Near Lund?

by Finn Valentin, Maria Theresa Larsen and Nicolai Heineke, Research Centre on Biotech Business

Effects on Academia-Industry Collaboration of Extending University Property Rights

[N.B. Newer version of this paper is found as working paper 2006-03]

by Finn Valentin and Rasmus Lund Jensen, Research Centre on Biotech Business

Building Regional Competencies: The Industrial Enzymes Industry

By Jesper Norus, Research Centre on Biotech Business, Copenhagen Business School

Patchworking Network Structures

By Jesper Norus, Research Centre on Biotech Business, Copenhagen Business School

Roadmapping as a Tool for Renewing Regulatory Practices: The Case of Stem Cells

By Kristian Borcha* and Jesper Norus', *Systems Analysis Department, Risø National Laboratory and 'Research Centre on Biotech Business, Copenhagen Business School

Heterogeneity of Intellectual Assets: A Method for Identification and Measurement with Patent Data

By Henrich Dahlgren, Rasmus Lund Jensen and Finn Valentin, Research Centre on Biotech Business, Copenhagen Business School

Pushing the Envelope: Self-organised Selective Involvement of Public Science in Industrial Biotechnology

By Finn Valentin and Rasmus Lund Jensen, Research Centre on Biotech Business, Copenhagen Business School

What About Innovation Collaboration in Biotech Firms? Revisiting Occurence and Spatial Distribution

By Maureen McKelvey, Chalmers University of Technology, Sweden

Profiles of Four Projects in Biotech Business

By Finn Valentin, Research Centre on Biotech Business, Copenhagen Business School

Finn Valentin and Rasmus Lund Jensen: Discontinuities and distributed innovation – The case of biotechnology in food processing in Ken Green, Marcela Miozzo and Paul Dewick (eds.) Technology, Knowledge and the Firm: Implications for Strategy and Industrial Change. Cheltenham Edward Elgar, January 2005

This paper examines the organisation of distributed innovation shaped by the major discontinuity in the life sciences and their associated technologies that has unfolded over the past 3 decades. While most studies have focused on its effects on pharmaceutical R&D this paper studies food processing technologies, taking biotech exploitation of the ubiquitous micro-organism of Lactic Acid Bacteria as its example. Patents provide most of the data. Although highly distributed forms of innovation emerge from 1980 onwards, incumbents introduce virtually all innovations in this field, while the role of Dedicated Biotechnology Firms remains negligible. Public Research Organisations contribute significantly to distributed R&D, and to a limited extent do they also take on the role of economic actors. To explain the organisational characteristics of this distributed innovation this paper suggests a distinction between definition and solution of innovation problems. Extending Simon’s analysis of complex problems it is argued that definition and problem solving in innovation need not have same levels of decomposability Using text-mining tools on patent abstracts the paper demonstrates the low decomposability of problem definition in food LAB biotech innovation. Differential access to this problem definition is argued to give rise to considerable variability in the role taken by different actors in distributed innovation, including the virtual absence of DBFs. By implication, the US model for biotech growth, emphasising the market mechanisms of DBF-formation, venture capital and scientist entrepreneurs, should not incautiously be pursued in all contexts and for all applications of biotechnology. Low decomposability of problem definition in innovations may preclude the emergence of these vehicles for market-driven growth, and in such cases distributed innovation must take other forms, including not least an active role of public science.

Finn Valentin and Rasmus Lund Jensen: Networks and technology systems in science-driven fields. The case of European biotechnology in food ingredients in Laage-Hellman, Jens; McKelvey, Maureen and Rickne, Annika (eds.) The Economic Dynamics of Modern Biotechnologies: Europe in Global Trends. Cheltenham: Edward Elgar Publishing, June 2004

This paper studies food processing biotechnology, taking Lactic Acid Bacteria (LAB) as its case, a microorganism widely employed in food processing. Tracking biotech patents in this field since 1980 we observe a European rate of innovation notably above the US level. The high European performance furthermore comes out of a few mutually disconnected innovation systems, each with strong internal linkages. Competing theories on systems of innovation are examined to explain the global organisations of this field of biotech R&D. In their timing and in their actor configuration LAB innovation systems evolve in response to specific cognitive characteristics of R&D. Their structural characteristics at the same time reflect the strong economic competence of a few large multinational food corporations. Together these system characteristics indicate Technology Systems (TS) theory as the more relevant theoretical compared to the alternative interpretation offered by the framework of “National Systems of Innovation” (NSI). Using formal networks analysis the chapter suggest novel ways of differentiating TS and NSI as distinct, yet interrelated causal mechanisms. These interrelationships have implication for our understanding of the responsiveness and flexibility of institutions, particularly those associated with production and dissemination of knowledge.

Finn Valentin and Per Vejrup-Hansen: Udvikling af Videnservice. Copenhagen: Nyt Teknisk Forlag Nov, 2004 (296 pp in Danish)

The book examines how new types of services are developed by Danish engineering consultancy firms, analysing how they address the challenge of knowledge creation as part of the process of diversifying into new lines of business. Finn Valentin backs up his analysis of this double helix of business and knowledge creation by also offering systematic presentation of 11 case studies of novel services. Per Vejrup-Hansen presents a statistical analysis of engineers’ mobility within knowledge-intensive services and of the effect of knowledge heterogeneity on firm performance.